地方性氟骨症是一种以骨质增加为主的骨代谢和骨重建机制紊乱的一种地方病。骨形态计量学是指从微观结构观察骨的形态变化(包括骨小梁、骨皮质、骨细胞的变化等)。他们从不同的侧面反映骨的生理特性和病理特点,是测量骨量的重要手段之一。美国食品和药品管理局(FDA)把用骨组织形态计量学的方法观察药物对去卵巢大鼠骨形态计量学的改变作为评 Local skeletal fluorosis is a endemic disease characterized by an imbalance of bone metabolism and bone remodeling that predominantly increases bone mass. Bone morphometry refers to the observation of the morphological changes of the bone (including trabecular bone, cortical bone, changes in bone cells, etc.) from the microstructure. They reflect the physiological characteristics and pathological features of bone from different aspects and are one of the important means to measure bone mass. The US Food and Drug Administration (FDA) used bone histomorphometry to observe changes in bone morphometry in ovariectomized rats as a