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目的:探讨认知行为疗法(cognitive behavior therapy, CBT)对糖尿病肾病患者营养状况及血糖和肾功能的影响。方法:选取我院2018年1月至2019年6月收治的糖尿病肾病患者102例,采用随机数字表法分为常规治疗组和认知行为治疗组,每组各51例。常规治疗组给予常规饮食和药物治疗,认知行为治疗组加用CBT。3个月后对比两组患者临床疗效、营养状况、血糖水平及肾功能。结果:认知行为治疗组患者治疗总有效率为96.07%,高于常规治疗组的76.47%(n P<0.05);治疗后两组患者ALB、PA、TRF、Hb均较治疗前升高,且认知行为治疗组升高幅度高于常规治疗组(n P<0.05);治疗后两组患者HbA1c、BUN、SCR均较治疗前降低,且认知行为治疗组降低幅度高于常规治疗组(n P<0.05)。n 结论:CBT能够改善糖尿病肾病患者的营养状况、血糖水平和肾功能,提高肾脏对葡萄糖的摄取和利用,降低血糖水平,减轻并发症,值得推广。“,”Objective:To investigate the effect of cognitive behavioral therapy (CBT) on nutritional status, blood glucose and renal function in patients with diabetic nephropathy.Methods:A total of 102 patients with diabetic nephropathy in our hospital from January 2018 to June 2019 were randomly selected and divided into conventional treatment group and cognitive treatment group with 51 subjects in each group. The conventional treatment group was given conventional diet and drug treatment, while the cognitive treatment group was given CBT in addition to the conventional treatment. The clinical efficacy, nutritional status, blood glucose and renal function were compared after 3 months’ treatment.Results:The total effective rate of cognitive treatment group was 96.07%, which was higher than that of the conventional treatment group(76.47%; n P<0.05). The levels of ALB, PA, TRF and Hb of two groups were increased after treatment, and the increase range of cognitive treatment group was higher than that of the conventional treatment group (n P<0.05). The levels of HbA1c, BUN and Scr of two groups of patients were decreased after treatment, and the decrease degree of cognitive treatment group was higher than that of conventional treatment group (n P<0.05).n Conclusion:CBT can improve the nutritional status, decrease blood glucose and improve renal function of diabetic nephropathy patients. After intervention, CBT can improve the uptake and utilization of glucose in kidney, reduce blood glucose level and reduce complications, which is worthy of promotion.