几十年前,人们已经认识到消化性溃疡与不伴有低血糖症的胰腺胰岛细胞瘤的关系,卓—艾氏首次提出在消化性溃疡和(或)腹泻综合征以及胰腺非β胰岛细胞瘤中,高胃酸分泌在消化过程中是一种重要的病理生理因素,并认为胂癌中可能释放一种激素引起胃酸分泌过高,这就是后来发现的胃泌素.随着放免技术的发展,得知在这些病人体内具有循环状态的高胃 Decades ago, people have recognized the relationship between peptic ulcer and pancreatic islet cell tumor without hypoglycemia, Zhuo-Ai’s first proposed in peptic ulcer and (or) diarrhea syndrome and pancreatic non-beta islet cells Tumor, high gastric acid secretion in the digestive process is an important pathophysiological factors, and that arsenic cancer may release a hormone cause hypersecretion of gastric acid, which is later found in gastrin. With the development of radioimmunoassay , Learned that in these patients have a circulating high stomach