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目的 为了提高重度急性有机磷农药中毒的抢救成功率 ,探讨换血治疗重度急性有机磷农药中毒的疗效。方法 对 3 6 0例重度急性有机磷农药中毒患者 ,随机分为换血组 (Ⅰ )和对照组 (Ⅱ )进行疗效对比。两组均接受阿托品及胆碱酯酶复能剂 (解磷定 )等综合治疗。Ⅰ组加用了换血治疗。结果 ( 1)胆碱酯酶 (CHE)活力恢复正常所需时间 ,Ⅰ组平均 5 6d ,Ⅱ组平均 11d ;( 2 )阿托品平均总用量Ⅰ组 ( 5 5 7 2± 12 6 7)mg ,Ⅱ组 ( 15 10 2± 78 83 )mg ,Ⅰ组比Ⅱ组明显减少。 ( 3 )两组治疗效果比较Ⅰ组明显优于Ⅱ组。经统计学处理所有指标均差异显著。结论 重度急性有机磷农药中毒的治疗 ,换血组比对照组疗效更好。
Objective To improve the success rate of salvage of severe acute organophosphorus pesticide poisoning and to explore the effect of transfusing blood for the treatment of severe acute organophosphorus pesticide poisoning. Methods A total of 3600 patients with acute severe acute organophosphorus pesticide poisoning were randomly divided into transfusion group (Ⅰ) and control group (Ⅱ). Both groups received atropine and cholinesterase agent (Phosphate) and other comprehensive treatment. Group Ⅰ added a transfusion treatment. Results (1) Cholinesterase (CHE) vitality returned to normal time, group Ⅰ average 56 days, group Ⅱ average 11 days; (2) the average total amount of atropine group Ⅰ (5 572 ± 12 6 7) mg, Ⅱ group (15 10 ± 78 83) mg, Ⅰ group than in Ⅱ group was significantly reduced. (3) Comparison of the two groups of treatment group Ⅰ was significantly better than Ⅱ group. Statistical analysis of all indicators were significant differences. Conclusion Severe acute organophosphorus pesticide poisoning treatment, transfusion group better than the control group.