肥胖、糖尿病(非胰岛素依赖型)常合并有高血压,多数人指出三者相互并发率很高。其病理过程均与胰岛素耐受性有关。关于肥胖和糖尿病患者对胰岛素耐受性的研究很多,但高血压与胰岛素的关系报道较少。Modan等曾经从葡萄糖耐量试验胰岛素的反应加以探讨,最近,Ferrannini等运用血糖正常的胰岛素夹(euglycemic insulin clamp)进行研究,得出最确切的结论,本文对此作一介绍。研究对象为13名较年轻的肥胖和无糖耐量低下的原发性高血压患者(血压165±6/112±3mmHg)。在应用定型夹心法测定胰岛素耐受性的同时,进行~8H标 Obesity, diabetes (non-insulin-dependent) often associated with high blood pressure, most people point out that the three are very high concurrency with each other. The pathological process is related to insulin resistance. There are many studies on insulin resistance in obese and diabetic patients, but there are few reports on the relationship between hypertension and insulin. Modan et al. Have explored the effects of insulin resistance in glucose tolerance tests. Recently, Ferrannini et al. Used euglycemic insulin clamps to study and concluded the definitive conclusion, which is presented in this article. The subjects were 13 younger hypertensive patients with obesity and impaired glucose tolerance (blood pressure 165 ± 6/112 ± 3 mmHg). In the application of stereotypes determination of insulin resistance at the same time, to ~ 8H standard