论文部分内容阅读
众所周知异核二维实验在中、小分子的结构确定中非常重要 .例如1H与13C/ 15 N异核远程相关无疑是连接分子中孤立结构碎片及季碳的最有利的工具 .然而 ,在间接检测的异核二维实验中 ,间接检测域 异核维的太低分辨率一直是困扰着化学家的主要问题 .过去在有限的采样时间内提高分辨率的方法主要有线性预测、带选择脉冲和控制好的折叠 3种方法 .文中介绍一种最新开发出的利用Hadamard激发雕刻的方法 .借助Varian核磁共振系统的高品质射频系统和灵活的软件工具 ,用户可以方便的实施新的激发雕刻方案 ,极大地改善 gHMBC实验的F1分辨率 .
It is well-known that heteronuclear two-dimensional experiments are very important in determining the structure of medium and small molecules, for example, the long-term correlation between 1H and 13C / 15N heterokaryons is undoubtedly the most favorable tool for linking isolated structural fragments and quaternary carbon in molecules. However, Detection of heteronuclear two-dimensional experiments, indirect detection of heterostructured dimension too low resolution has been plagued chemists major problems in the past in the limited sampling time to improve the resolution of the main methods are linear prediction, with a selection pulse And controlled folding of the three methods.This article describes a newly developed Hadamard excitation engraving method with Varian nuclear magnetic resonance system of high-quality radio frequency system and flexible software tools, users can easily implement the new excitation engraving program , Greatly improving the F1 resolution of the gHMBC experiment.