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Nahmias等在1971年首先提出TORCH的概念,即弓形体(toxoplasma)、风疹病毒(rubella virus)、巨细胞病毒(cytomegalovirus,CMV)和单纯疱疹病毒(herpes simples virus,HSV)4个引起胎儿先天性感染的病原微生物英文名称首字母组合。尽管为同一组微生物,但是它们在病原学、致病机制、免疫学、实验室诊断方法、治疗选择和预防(包括疫苗)等方面有着显著差异。因此,如果捆绑TORCH组合项目对孕妇进行血清学筛查,既缺乏科学依据、浪费有限的医疗资源,同时许多血清学筛
Nahmias et al. First proposed the concept of TORCH in 1971. Four toxoplasma, rubella virus, cytomegalovirus (CMV) and herpes simples virus (HSV) caused congenital Infected with the initials of English names of pathogenic microorganisms. Despite the same group of microorganisms, they have significant differences in etiology, pathogenesis, immunology, laboratory diagnostic methods, treatment options and prophylaxis (including vaccines) and the like. Therefore, if the TORCH combinatorial program is used for serological screening of pregnant women, there is a lack of scientific evidence to waste limited medical resources while many serological screens