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目的:观察自拟中药骨疏散对绝经后骨质疏松患者血清雌激素水平及骨密度的影响。方法:选择珠海市妇幼保健院2012年8月~2013年12月绝经后骨质疏松症患者96例,随机分为治疗组与对照组各48例,治疗组应用自拟中药骨疏散治疗;对照组应用福善美(阿伦磷酸钠)治疗。对照分析两组患者治疗前后血清雌激素水平及第二腰椎骨密度值指标。结果:治疗后两组患者血清雌二醇(E2)水平、腰椎骨密度值均显著升高,差异具有统计学意义;两组患者治疗后血清E2、腰椎骨密度值(g/cm3)水平比较,差异无统计学意义。结论:自拟中药骨疏散及福善美均能提升绝经后骨质疏松患者血清雌激素水平、增加腰椎骨密度。
Objective: To observe the effect of self-made traditional Chinese medicine bone evacuation on serum estrogen level and bone mineral density in postmenopausal osteoporosis patients. Methods: 96 cases of postmenopausal osteoporosis were selected from Zhuhai MCH center from August 2012 to December 2013. They were randomly divided into treatment group (48 cases) and control group (48 cases). The treatment group Group application Fosamax (alendronate sodium) treatment. The levels of serum estrogen and the second lumbar spine BMD before and after treatment were compared between the two groups. Results: Serum estradiol (E2) level and lumbar spine BMD were significantly increased in both groups after treatment, the difference was statistically significant; serum E2 and lumbar BMD (g / cm3) were significantly lower in both groups after treatment ,The difference was not statistically significant. CONCLUSION: Self-made traditional Chinese medicine bone evacuation and Fushanmei can both increase serum estrogen level and increase lumbar spine BMD in postmenopausal osteoporosis patients.