慢性阻塞性肺疾病患者诱导痰液中IL-6和IL-8水平变化的临床意义

来源 :实用临床医药杂志 | 被引量 : 0次 | 上传用户：anonyjim

【摘要】

：

目的探讨慢性阻塞性肺疾病（COPD）患者诱导痰液中白细胞介素-6（IL-6）和白细胞介素-8（IL-8）水平变化的临床意义。方法选取COPD患者35例为COPD组,另选取健康体检者40例为健康组,根据有

【作者】

：

宋晓萍裴复阳

【机构】

：

大连大学附属中山医院呼吸内科

【出处】

：

实用临床医药杂志

【发表日期】

：

2016年5期

【关键词】

：

慢性阻塞性肺疾病诱导痰液白细胞介素-6 白细胞介素-8 呼吸功能 chronic obstructive pulmonary disease induce

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目的探讨慢性阻塞性肺疾病（COPD）患者诱导痰液中白细胞介素-6（IL-6）和白细胞介素-8（IL-8）水平变化的临床意义。方法选取COPD患者35例为COPD组,另选取健康体检者40例为健康组,根据有无吸烟史分为无吸烟22例和吸烟18例。2组受试者行肺功能检测,运用诱导痰液方法收集痰液,酶联免疫吸附试验（ELISA）测定痰液上清中IL-6和IL-8水平变化,Spearman相关性检验分析IL-6、IL-8水平与肺功能的相关性。结果 COPD组诱导痰液中性粒细胞百分比显著高于健康组无吸烟者和吸烟者（P〈0

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慢性阻塞性肺疾病患者诱导痰液中IL-6和IL-8水平变化的临床意义

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