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目的通过肌钙蛋白I(cTnI)、肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)在急性心肌梗死(AMI)诊断中的比较研究,探讨各指标对于在心肌梗死诊断中的应用价值。方法将63例AMI患者分成未溶栓组和溶栓再通组,采用Access全自动微粒子化学发光免疫分析系统,检测两组患者血清cTnI、CK、CK-MB的检出时间、达到高峰时间及恢复时间,进行统计学处理及分析比较。结果cTnI升高对急性心肌梗死诊断的灵敏度高于CK、CK-MB;在心肌梗死后cTnI的增高和峰值出现时间均先于CK和CK-MB,且增高持续时间长。结论cTnI的检测有助于早期诊断AMI,对延迟入院的AMI患者检测cTnI也有重要意义。
Objective To compare the diagnostic value of cTnI, CK and CK-MB in the diagnosis of acute myocardial infarction (AMI) The application value. Methods Sixty-three patients with AMI were divided into two groups: untreated group and thrombolytic group. The detection system of serum total cTnI, CK and CK-MB in patients with AMI was achieved by using Access Automated Particle Chemiluminescence Immunoassay System Recovery time, statistical analysis and analysis. Results The increased sensitivity of cTnI was higher than that of CK and CK-MB in the diagnosis of acute myocardial infarction. The increase of cTnI and the peak appearance time of myocardial infarction were both earlier than that of CK and CK-MB after myocardial infarction. Conclusions The detection of cTnI is helpful for the early diagnosis of AMI. It is also of great significance for the detection of cTnI in patients with delayed admission of AMI.