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急性白血病(AL)患者由于自身疾病和反复化疗所致免疫功能及造血功能受抑,一般抗病力下降,极易发生医院内感染,成为AL最常见的并发症和死亡的主要原因之一。本文通过对127例AL患儿的医院感染情况分析,发现患者院内感染率为60.63％,感染直接死亡率为4.72％。感染部位为呼吸道感染,其次为口腔溃疡、败血症等,发现院内感染与治疗阶段,外周血白细胞计数、辅助治疗有密切关系;而与白血病的类型、常规应用抗生素等关系不明显。揭示在急性白血病的化疗过程中,诱导缓解期应住隔离病房,加强辅助治疗;尽量减少侵袭性操作。加强皮肤护理及口腔护理,减少内源性感染。
Acute leukemia (AL) patients due to their own disease and repeated immune response caused by chemotherapy and hematopoietic suppression, the general resistance to decline, prone to nosocomial infections, AL has become the most common complication and one of the major causes of death. In this paper, 127 cases of AL in children with hospital infection analysis found that the rate of nosocomial infection in patients was 60.63%, the direct infection rate was 4.72%. Infection sites were respiratory infections, followed by oral ulcers, sepsis and other found nosocomial infection and treatment stage, peripheral blood leukocyte count, adjuvant therapy are closely related; and the type of leukemia, routine use of antibiotics and other obvious. Revealed in the chemotherapy of acute leukemia, induced remission should live in isolation wards, to enhance adjuvant therapy; minimize invasive operation. Strengthen skin care and oral care to reduce endogenous infections.