论文部分内容阅读
[目的]探讨胸腔积液T淋巴细胞亚群检测对恶性病变的诊断价值。[方法]用流式细胞仪对28例肺癌和23例良性病变的患者胸腔积液T淋巴细胞亚群分析。[结果]中央型肺癌组胸腔积液CD3+CD4+(46.21±11.57)%、CD3+CD8+(52.33±10.78)%和CD4+/CD8+(0.97±0.36),周围型肺癌组胸腔积液中胸腔积液CD3+CD4+(42.35±9.59)%、CD3+CD8+(57.85±9.76)%和CD4+/CD8+(0.81±0.41),良性病变组胸腔积液CD3+CD4+(63.45±7.31)%、CD3+CD8+(32.54±7.12)%和CD4+/CD8+(2.14±0.31),前两组差异无统计学意义(P﹥0.05)。前两组显著低于良性病变组,P﹤0.05。[结论]胸腔积液T淋巴细胞亚群的改变对良恶性病变的鉴别诊断有重要的意义。
[Objective] To investigate the diagnostic value of detecting pleural effusion T lymphocyte subsets in malignant lesions. [Methods] The subsets of T lymphocytes in pleural effusion of 28 lung cancer patients and 23 benign lesions were analyzed by flow cytometry. [Results] The rates of CD3 + CD4 + (46.21 ± 11.57)%, CD3 + CD8 + (52.33 ± 10.78)% and CD4 + / CD8 + (0.97 ± 0.36) in pleural effusion of central lung cancer group The percentage of CD3 + CD4 + (42.35 ± 9.59)%, CD3 + CD8 + (57.85 ± 9.76)% and CD4 + / CD8 + (0.81 ± 0.41) ± 7.12)% and CD4 + / CD8 + (2.14 ± 0.31) respectively. There was no significant difference between the two groups (P> 0.05). The former two groups were significantly lower than the benign group, P <0.05. [Conclusion] The change of T lymphocyte subsets in pleural effusion is of great significance in the differential diagnosis of benign and malignant lesions.