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目的:研究高尿酸血症对早发冠心病的影响。方法:选取经Judkins法冠脉造影确诊为早发冠心病患者164例作为病例组,对照组为同期住院相同年龄段的非心脑血管病患者126例。空腹采集静脉血。结果:病例组BUA、FPG、TC、LDL-C均高于对照组(P均<0.05),调整其他危险因素后,高尿酸血症与早发冠心病仍呈正相关。结论:高尿酸血症是早发冠心病的危险因素之一,两者存在明显相关性。
Objective: To study the effect of hyperuricemia on premature coronary heart disease. Methods: Totally 164 cases of patients with premature coronary heart disease diagnosed by Judkins’ coronary angiography were selected as the case group. The control group was 126 cases of non-cardiovascular and cerebrovascular diseases of the same age hospitalized in the same period. Fasting blood samples were collected. Results: BUA, FPG, TC and LDL-C in case group were higher than those in control group (all P <0.05). After adjustment for other risk factors, hyperuricemia still had a positive correlation with premature coronary heart disease. Conclusion: Hyperuricemia is one of the risk factors for premature coronary heart disease, and there is a clear correlation between the two.