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[目的]探讨肥胖患者发生结直肠腺瘤的相关危险因素。[方法]收集行结肠镜检查的86例患者的临床资料,根据体质指数水平分为肥胖组和对照组,检测各组患者血脂、空腹血糖及空腹胰岛素水平,稳态模型计算胰岛素抵抗指数(homeostasis model assessment for insulin resistance,HOMA-IR)。[结果]肥胖组结直肠腺瘤阳性率、体质指数、三酰甘油、总胆固醇及HOMA-IR水平均高于对照组(P<0.05),Logistic回归分析显示体质指数、HOMA-IR和三酰甘油与结直肠腺瘤相关。[结论]肥胖患者体质指数、HOMA-IR和三酰甘油水平升高是结直肠腺瘤的危险因素。
[Objective] To explore the related risk factors of colorectal adenoma in obese patients. [Methods] The clinical data of 86 patients undergoing colonoscopy were collected and divided into obesity group and control group according to the level of body mass index. The levels of serum lipids, fasting blood glucose and fasting insulin in each group were measured. The homeostasis index model assessment for insulin resistance, HOMA-IR). [Results] The positive rates of colorectal adenoma, body mass index, triglyceride, total cholesterol and HOMA-IR in obese group were higher than those in control group (P <0.05). Logistic regression analysis showed that body mass index, HOMA- Glycerol is associated with colorectal adenomas. [Conclusion] The elevated body mass index, HOMA-IR and triglyceride in obese patients are risk factors of colorectal adenoma.