论文部分内容阅读
MOPP 是治疗晚期何杰金氏病最常用而有效的联合化疗方案,大约有70%病人可获完全缓解。但对于以 MOPP 首次治疗无效或完全缓解后复发的病人,其治疗相当困难,往往因病变发展而死亡。SCAB 方案是链脲霉素(streptozotocin)500mg/M~2,静注,第1～5天;环已亚硝脲(CCNU)100mg/M~2,第1天口服;阿霉素(adriamycin)45mg/M~2,第1天静注;博莱霉素(bleomycin)15mg/M~2,第1～8天肌注。这4种药物均没有包括在 MOPP 方案中。对以前治疗过的复治病人,其有效率为59%,完
MOPP is the most commonly used and effective combination chemotherapy for the treatment of advanced Hodgkin’s disease, and about 70% of patients receive complete remission. However, for patients who relapse after the initial treatment or complete remission of MOPP, the treatment is rather difficult and often dies as the disease progresses. SCAB regimen is streptozotocin 500mg / M ~ 2, intravenous injection, the first to fifth days; Central nitrosourea (CCNU) 100mg / M ~ 2, the first day of oral; adriamycin 45mg / M ~ 2, the first day of intravenous; bleomycin (bleomycin) 15mg / M ~ 2, 1 to 8 days intramuscular injection. None of these 4 drugs are included in the MOPP regimen. The treatment of re-treatment of patients previously, the effective rate of 59%, finished