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应用ＡＢＣ免疫组化法研究胰腺癌组织中ＮＭ２３蛋白的表达及意义。４１例胰腺癌ＮＭ２３蛋白阳性表达率５９％（２４／４１）；高分化、组织学分级Ⅰ级和未转移胰腺癌ＮＭ２３蛋白阳性表达率和核着色阳性病例率均明显地高于低分化、组织学分级Ⅲ级和转移的胰腺癌。结果提示ＮＭ２３蛋白表达可能与胰腺癌转移及潜在转移有密切关系，ＮＭ２３蛋白可能是反映胰腺癌生物学行为和预后的重要标记物
ABC immunohistochemistry was used to study the expression of NM23 protein in pancreatic cancer and its significance. The positive expression rate of NM23 protein in 41 cases of pancreatic cancer was 59% (24/41); the positive rate of NM23 protein positive and nuclear staining positive cases in well-differentiated, histological grade I and non-metastatic pancreatic cancer were significantly higher than those in poorly differentiated, Grade III grade and metastatic pancreatic cancer. The results suggest that the expression of NM23 protein may be closely related to the metastasis and potential metastasis of pancreatic cancer. NM23 protein may be an important marker reflecting the biological behavior and prognosis of pancreatic cancer.