幽门螺杆菌感染耐药的一种新观念

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幽门螺杆菌(H.pylori)感染常被认为是胃肠道疾病而不是感染性疾病.与其他可治愈的严重细菌感染相比,H.pylori感染的根除率较低.多数细菌感染性疾病根据药敏试验结果而行治疗,第一个疗程的预期根除率应>95%,典型感染应>99%.临床医师应根据当地微生物的耐药谱来制定初始治疗方案,并根据细菌培养结果进一步调整治疗方案.但医师们通常不清楚该地区H.pylori耐药的分布情况,因此尽管期望较高的H.pylori根除率,但疗效普遍较差.
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