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[目的]了解血清果糖胺(FMN)、血糖与糖尿病(DM)患者的临床变化及意义。[方法]对205例患者分单纯糖尿病组,DM肾病组和DM肝病组患者及50例正常对照组分别进行血清FMN,空腹血糖(FBG)和血清白蛋白(ALB)检测,并对单纯DM患者再进行餐后2h血糖及FMN测定。[结果]单纯DM患者空腹及餐后FMN与对照组之间差异都有统计学意义(P﹤0.001,P﹤0.001),而单纯DM患者组的空腹与餐后FMN差异无统计学意义(P﹥0.05);患者FMN与FBG及餐后2h血糖呈正相关(r=0.57,P﹤0.01;r=0.60,P﹤0.001)。[结论]FMN与血糖关系密切,联合检测对DM患者的诊断及疗效监测有重要的临床意义。
[Objective] To understand the clinical significance and clinical significance of serum fructosamine (FMN), blood glucose and diabetes mellitus (DM). [Methods] Serum FMN, fasting blood glucose (FBG) and serum albumin (ALB) were detected in 205 patients with diabetes mellitus, DM nephropathy and DM liver disease and 50 normal controls. The DM patients Then 2h postprandial blood glucose and FMN determination. [Result] The fasting and postprandial FMN in DM patients were significantly different from those in control group (P <0.001, P <0.001), but there was no significant difference between fasting and postprandial FMN in DM patients > 0.05). There was a positive correlation between FMN and FBG and 2h postprandial blood glucose (r = 0.57, P <0.01; r = 0.60, P <0.001). [Conclusion] FMN is closely related to blood glucose. It has important clinical significance for the diagnosis and curative effect monitoring of DM patients.