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稀土毒理学以及稀土离子作为钙离子的探针的研究受到普遍关注,人们对稀土离子的生物化学性质进行了广泛研究.作者曾报到了金属离子对DPPC脂质体的极性头构象的影响.鞘磷脂是神经组织细胞膜的重要磷脂组分,和DPPC有相似的极性头.本文利用核磁共振结合Raman光谱研究了金属离子对鞘磷脂脂双层的极性头构象的影响.1 材料和方法
Rare earth toxicology and rare earth ions as a probe of calcium ions have received widespread attention, and extensive research has been conducted on the biochemical properties of rare earth ions. The authors have reported the effect of metal ions on the polar head conformation of DPPC liposomes. Sphingomyelin is an important phospholipid component of nerve cell membrane and has a similar polarity head to DPPC.In this paper, the effect of metal ions on polar head conformation of sphingomyelin lipid bilayer was studied by 1H NMR and Raman spectroscopy.1 Materials and Methods