病人,女,60岁.因面部及四肢发生痛性红斑1周,发热5d入院.入院前1周无明显诱因于双手、足及膝部突然出现数个黄豆至蚕豆大的红斑与结节,皮疹迅速扩展成疼痛性红色斑块,2d后面及耳后亦发生同样皮疹,伴发热及肘、膝关节酸痛而来我院就诊.起病前无全身症状,既往身体健康,无其它系统疾病及药物过敏史. Patient, female, aged 60. One week after the onset of painful erythema on the face and extremities, 5 days after admission to hospital for fever, there was no obvious incentive for one week before hospitalization. Erythema and nodules suddenly appeared in several hands, feet and knees, The rash rapidly expanded into painful red plaques, and the same rash occurred on the back of the ears and behind the ears in the 2nd day, accompanied by fever and pain in the knees and knees. No systemic symptoms, no previous systemic diseases, Drug allergy history.