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目的:探讨过敏性疾病的致病因素。方法:应用免疫变态反应检测(invitrotest,IVT)方法检测102例患儿血清总IgE及6项特异性IgE,同时用乳胶增强速率散射比浊法(BNprospec)定量测定血清IgE,并将两种检测结果对比。结果:总IgE阳性59例(57.8%)。其中支气管哮喘中总IgE阳性率最高,达80.9%,其次是荨麻疹、喘息性支气管炎、支气管炎、肺炎、上呼吸道感染等。各种过敏原中,居首位是螨虫,其他依次是风杨、梧桐、蟑螂等。过敏性疾病中以1种过敏原阳性占多数,3种或3种以上者少。本资料还提示,IVT检测法的IgE阳性率与BNprospec法检出的升高率无显著差异。结论:IVT可明确检出特异性过敏原,为疾病的病因诊断提供客观依据。
Objective: To explore the risk factors of allergic diseases. Methods: Serum total IgE and 6 specific IgE in 102 children were detected by the method of invitrotest (IVT). Serum IgE levels were measured by latex enhanced rate nephelometry (BNProspec), and the serum levels of IgE, Comparative Results. Results: The total IgE positive in 59 cases (57.8%). Bronchial asthma in which the highest positive rate of total IgE, up to 80.9%, followed by urticaria, asthmatic bronchitis, bronchitis, pneumonia, upper respiratory tract infection. Among the various allergens, the first is mites, followed by the wind Yang, Indus, cockroaches and so on. Allergic diseases in a positive allergen accounted for the majority, three or more than three less. The data also prompts, IVT test IgE positive rate and BNprospec law detected no significant difference in the rate of increase. Conclusion: IVT can detect specific allergens clearly and provide an objective basis for the etiological diagnosis of the disease.