谷胱甘肽-s-转移酶(GST)是一种多功能的Ⅱ相代谢酶家族,也是一个同源二聚体酶的超基因家族,普遍存在于各种生物体内。在哺乳动物各组织中均含有不同种类的GST,其含量和活性亦各不相同。GST可分为膜结合微粒体家族和胞质家族2大类。哺乳动物GST至少具有8类同工酶:α、δ、κ、π Glutathione-S-transferase (GST) is a multifunctional family of phase II metabolic enzymes and a super-gene family of homodimeric enzymes commonly found in various organisms. Different mammalian tissues contain different types of GST, its content and activity are also different. GST can be divided into membrane-bound microsomal family and cytoplasmic family 2 categories. Mammalian GST has at least eight classes of isozymes: α, δ, κ, π