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本文对不同发病强度地区的健康人群的乙脑抗体水平进行了检测。结果发现不同地区健康人群的乙脑抗体水平有明显差异,乙脑高发区人群的抗体阳性率及GMT明显高于中发疫区和低发疫区的人群。而且乙脑抗体阳性率的高低与发病率无相关关系存在。不同年龄组人群的抗体阳性率有随年龄增长而增加的趋势。大年龄组人群的隐性感染率高于低年龄组,可能与暴露机会较多有关。在流行期,每个年龄组人群都被感染。流行期前体内无抗体或滴度较低者,感染率高于体内高滴度者。提示人群滴度达到一定程度后受到再次感染的机会相对减少。健康人群的阳性率普遍低于文献报道的达到保护作用的阳性率,因此,乙脑疫苗的注射应给予加强。
In this paper, the detection of JE antibody levels in healthy population in different areas of endemicity. The results showed that there were significant differences in the antibody levels of Japanese encephalitis among healthy population in different areas. The antibody positive rate and GMT in the population with high incidence of Japanese encephalitis were significantly higher than those in the middle and low prevalence areas. And there is no correlation between the positive rate of JE antibody and the incidence. Antibody positive rate in different age groups increased with age. The prevalence of latent infection in older age groups is higher than in younger age groups and may be related to more exposure. During the epidemic, every age group is infected. Pre-epidemic no antibodies or titers in vivo, the infection rate is higher than the high titers in vivo. Tip population titers reach a certain level after the chance of being infected again relatively reduced. The positive rate of healthy population is generally lower than the reported positive rate of protection, therefore, JE vaccine should be given to strengthen the injection.