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作者指出,在脑电图(EEG)上所观察到的电活性主要是由神经元结构所产生,基本上反映神经元的状态,而胶质细胞对EEG电现象不产生直接影响。但它们居于脑神经元与行细血管之间,与血—脑间物质交换有关,对神经元的代谢有肯定的影响,无疑对EEG有间接影响。作者企图研究药物对神经元活性及血脑屏障功能产生分化作用的可能性。 实验采用乌拉坦麻醉的家兔。于两侧大脑的对称部位描记脑电。结扎一侧颈总动脉的近心端及颈外动脉等分支,插入套管,以相当于血压的压力从套管灌注药物至一侧大脑,另一
The authors point out that the electrical activity observed on EEG is mainly generated by the neuronal structure and essentially reflects the state of the neurons, whereas glial cells do not have a direct effect on the EEG electronegativity. However, they live in the brain between the neurons and the line of thin blood vessels, and blood-brain matter exchange, the metabolism of neurons have a positive impact, no doubt on the EEG have an indirect impact. The authors attempted to study the potential of drugs to differentiate neuronal activity and blood-brain barrier function. Experimental rabbits anesthetized with urethane. Symmetrical parts of both sides of the brain traced EEG. One side of the common carotid artery ligation of the proximal end of the carotid artery and other branches, insert the cannula, with the pressure equivalent to blood pressure from the cannula infusion of drugs to one side of the brain, the other