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目的比较胸腔镜胸膜固定术与胸腔闭式引流术治疗大量恶性胸腔积液的应用效果。方法选取大量恶性胸腔积液患者72例,按随机数字表法分为两组,每组36例。对照组实施胸腔闭式引流术治疗,观察组给予胸腔镜胸膜固定术治疗,比较两组患者术后相关指标、治疗效果、并发症及复发情况。结果术后,观察组引流管留置时间、总蛋白定量、住院时间低于对照组,差异有统计学意义(P<0.05);观察组治疗效果优于对照组,观察组术后胸痛、发热及复发率低于对照组,差异有统计学意义(P<0.05)。结论与胸腔闭式引流术治疗比较,胸腔镜胸膜固定术治疗可提高大量恶性胸腔积液的治疗效果,降低术后不良反应发生率及复发率,缩短患者恢复时间。
Objective To compare the effect of thoracoscopic pleurodesis and thoracic closed drainage in the treatment of a large number of malignant pleural effusions. Methods A total of 72 patients with malignant pleural effusion were selected and divided into two groups according to random number table method, with 36 cases in each group. The control group was treated with closed thoracic drainage, and the observation group was treated with thoracoscopic pleurodesis. The related indexes, treatment effects, complications and recurrence were compared between the two groups. Results Postoperatively, drainage tube indwelling time, total protein quantitation and hospital stay in the observation group were significantly lower than those in the control group (P <0.05). The observation group was superior to the control group in the treatment effect. The postoperative chest pain, fever and The recurrence rate was lower than the control group, the difference was statistically significant (P <0.05). Conclusion Compared with thoracic closed drainage, thoracoscopic pleurodesis can improve the treatment effect of massive malignant pleural effusions, reduce the incidence of postoperative adverse reactions and recurrence rate and shorten the recovery time of patients.