目的:探讨胼胝体切开术治疗难治性癫痫的效果。方法:36例难治性癫痫行胼胝体切开术治疗,术后随访6个月~2 a。结果:满意10例(27.7%),显著改善13例(36.1%),良好5例(13.8%),效差6例(16.6%),无改善2例(5.6%),无死亡病例,达到良好以上者占77.7%。结论:全面性发作的患者致痫区往往比较广泛而无法切除,胼胝体切开有较好的治疗效果。 Objective: To investigate the effect of corpus callosotomy on refractory epilepsy. Methods: Thirty-six cases of refractory epilepsy were treated by corpus callosotomy. The patients were followed up for 6 months to 2 years. Results: Satisfactory results were obtained in 10 cases (27.7%), 13 cases (36.1%), 5 cases (13.8%) and 6 cases (16.6% 77.7% are good or above. Conclusion: The patients with generalized seizures often have epileptogenic region and can not be resected. The corpus callosum has better curative effect.