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目的：观察用丹参粉针剂佐治新生儿缺氧缺血性脑病（HIE）时血清脂质过氧化物（LPO）含量变化及临床疗效。方法：用比色法（721分光光度计）测定对照组和丹参组计90例新生儿HIE治疗前后的LPO，同时观察神经反射。结果：丹参组LPO下降比对照组明显．神经反射恢复快，丹参组轻、中度HIE治疗前后LPO下降明显。结论：丹参粉针剂是一有效的氧自由基（OFR）清除剂，具有降低LPO的作用，临床疗效优于对照组，值得临床推广应用。
Objective: To observe the change of serum lipid peroxide (LPO) content and the clinical curative effect in neonatal hypoxic-ischemic encephalopathy (HIE) treated with salvia miltiorrhiza injection. Methods: LPO of 90 neonates with HIE before and after treatment were determined by colorimetric method (721 spectrophotometer) and the reflexes were observed. Results: The decrease of LPO in salvia miltiorrhiza group was more obvious than that in control group. Nerve reflex fast recovery, Salvia group light, moderate HIE LPO decreased significantly before and after treatment. Conclusion: Danshen injection is an effective oxygen free radical (OFR) scavenger with the effect of reducing LPO. The clinical curative effect is better than that of the control group, which is worthy of clinical application.