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恶性肿瘤不仅是一种细胞增殖失控的疾病,而且是一种细胞死亡异常的疾病。人体内调节细胞增殖和死亡之间的平衡机制一旦被破坏,就可能发生肿瘤,这种增殖—死亡的平衡失调通常是由于细胞凋亡的调节紊乱引起。Survivin是一新发现的凋亡抑制基因,nm-23h1基因是与人类肿瘤转移密切相
Malignancy is not only a disorder of uncontrolled cell proliferation but also a disorder of abnormal cell death. Tumors can develop in the body once the balance mechanism of regulating cell proliferation and death is destroyed. The imbalance of proliferation-death balance is usually caused by disturbance of regulation of apoptosis. Survivin is a newly discovered inhibitor of apoptosis, the nm-23h1 gene is closely associated with human tumor metastasis