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目的探讨性别差异对高龄急性冠脉综合征患者经皮冠状动脉介入治疗预后的影响。方法回顾性分析80例85岁以上急性冠脉综合征患者,观察性别差异对住院期间和长期预后的影响。结果女性组高血压病、单支病变及DES植入比例略高;而既往心肌梗死史、既往冠脉介入治疗史、血脂异常、三支病变比例低于男性组。住院期间主要心血管不良事件(MACE)发生率要高于男性组(10.8%vs 7.0%;P>0.05)。随访1年时MACE发生率两组相似(5.7%vs 4.9%;P=0.10)。尽管80%患者仅植入1个支架,但1年生存率较高。结论高龄女性ACS接受PCI住院期间MACE发生率要高于男性,不完全血运重建策略仍可使这一特殊人群长期获益。
Objective To investigate the effect of gender differences on the prognosis of elderly patients with acute coronary syndrome undergoing percutaneous coronary intervention. Methods A retrospective analysis of 80 patients over 85 years of age with acute coronary syndromes and observed the gender differences in the duration of hospitalization and long-term prognosis. Results The prevalence of hypertension, single vessel disease and DES implantation was slightly higher in female patients. The history of prior myocardial infarction, previous coronary intervention, dyslipidemia, and three-vessel lesion were lower than those in male patients. The incidence of major cardiovascular adverse events (MACE) during hospitalization was higher in the male than in the male (10.8% vs 7.0%; P> 0.05). The MACE incidence at 1 year of follow-up was similar between the two groups (5.7% vs 4.9%; P = 0.10). Although 80% of patients have only one stent, the 1-year survival rate is higher. Conclusion The incidence of MACE in elderly women with ACS during hospital admission is higher than that in men. The incomplete revascularization strategy may still benefit this particular group in the long term.