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鹽酸普魯卡因注射液的含量测定除以有机溶剂CHCl_3提取游离的普魯卡因,然后加过量酸再以硷反滴外,其他尚有銀量法、直接用硷滴定的中和法、重氮法、溴量法等。提取法費时耗药,而其他各法则未將鹽酸普魯卡因在消毒或久貯时易于分解这一问题加以考虑,因不論用銀量法、中和法、重氮法或溴量法均同时將分解产物滴定在内。为了求出鹽酸普魯卡因的实际含量,一般文献多介绍將分解产物
Determination of the content of procaine hydrochloride injection divided by the organic solvent CHCl_3 extraction of free procaine, and then add excess acid and then the anti-drop, there are other silver method, the direct use of alkaline titration and neutralization method, Diazo method, bromine method and so on. Spending time-consuming extraction method, while the other rules do not proclauride hydrochloride in the disinfection or storage of a long time easy to decompose this issue to be considered, regardless of the amount of silver method, and the law, diazotization or bromine method At the same time will decomposition products titration included. In order to find the actual content of procaine hydrochloride, the general introduction of the literature will decompose the product