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近几年来,由于肝素生物学作用的多样性而被广泛地应用于慢性非特异性肺部疾患的治疗。实验和临床观察证明,肝素具有杀菌和抗病毒作用,增强抗菌疗效,阻止非特异性体液免疫机能下降,在细胞水平上直接参与防卫性的非特异性反应。此外,肝素尚可改善微循环,在慢性非特异性肺部疾患时,该品尚可消除高凝血和激活纤维蛋白溶解,具有明显的脱敏作用。为了评价在肺功能不全的病人治疗中,应用肝素吸入法的临床效果,作者将全部被观察的病人分成二个组进行比较。第一组(对照组)27例,传统疗法治疗;第二组(治疗组)49例,附加给予肝素气雾剂。
In recent years, due to the diversity of heparin biological effects, it has been widely used in the treatment of chronic nonspecific pulmonary diseases. Experimental and clinical observations prove that heparin has bactericidal and antiviral effects, enhances antibacterial efficacy, prevents the decline of nonspecific humoral immune function, and directly participates in defensive nonspecific reactions at the cellular level. In addition, heparin can improve microcirculation, in chronic non-specific lung disease, the product can still eliminate high blood coagulation and activation of fibrinolysis, with significant desensitization. To evaluate the clinical effect of heparin inhalation in the treatment of patients with pulmonary insufficiency, the authors divided all observed patients into two groups for comparison. The first group (control group) 27 cases, the traditional therapy; the second group (treatment group) 49 cases, additional administration of heparin aerosol.