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[答]一般认为肺心病主要侵犯右心,引起右心衰,但近来发现有10～30%的肺心病患者左心同时受累引起左心衰。其产生机理是: 1.缺氧使心内膜下乳酸堆积,高能磷酸合成降低,同样可使左心功能受损,心缩力减弱。 2.肺纤维化,肺动脉高压时,支气管动脉与肺静脉分流短路形成,回到左心血量增多,加重左心室负荷。
[A] Generally believed that pulmonary heart disease mainly infringement of the right heart, causing right heart failure, but recently found that 10 to 30% of patients with pulmonary heart disease left heart involvement caused by left heart failure. The mechanism is: 1. Hypoxia to subendocardial lactic acid accumulation, high energy phosphate synthesis decreased, the same can make left heart function impaired, reduced cardiac contractility. Pulmonary fibrosis, pulmonary hypertension, bronchial artery and pulmonary vein shunt short-circuit formation, back to the left heart blood volume increased, increased left ventricular load.