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目的研究探讨影响基层老年恶性肿瘤预防生存的多项相关因素,为基层老年恶性肿瘤的治疗提供有效安全途径。方法选取2005年2月—2009年2月的183例基层老年恶性肿瘤患者的基本临床资料进行回顾性分析,应用SPSS软件处理影响基层老年恶性肿瘤患者预后生存的各项相关因素。结果基层老年恶性肿瘤患者的食管癌、肺癌、肝癌和胃癌等发病率比较高,全组患者12个月、24个月和36个月的生存率分别为52.5%、15.3%、2.7%。肝癌患者1.8%行抗肿瘤治疗,81.8%放弃抗肿瘤治疗。肿瘤患者95.7%进行抗肿瘤治疗1-2个周期,没有顺利完成肿瘤综合治疗。单因素分析对老年恶性肿瘤的认知程度、经济因素、能否进行规范化和个体化的综合治疗、性别、年龄、肿瘤分期及并发症是影响老年恶性肿瘤预后生存的主要相关因素,多因素分析对老年恶性肿瘤的认知程度、经济因素、能否进行规范化和个体化的综合治疗是影响老年恶性肿瘤预后生存的独立因素。结论对老年恶性肿瘤的认知程度和经济因素是影响老年恶性肿瘤预后生存的最重要因素,基层医生对老年恶性肿瘤治疗的规范化及个体化知识的掌握程度也是影响基层老年恶性肿瘤预防的重要因素。性别、年龄、合并症、恶性肿瘤的病理类型及分期是影响老年恶性肿瘤预后生存期的相关因素。加强对老年恶性肿瘤科普知识的宣教和基层肿瘤专科医生的规范化及个体化治疗专业知识的培训是治疗老年恶性肿瘤的当务之急。
Objective To study the factors that influence the prevention of survival of primary malignant tumors in the grass roots and provide an effective and safe way for the treatment of primary malignant tumors in the grass roots. Methods The clinical data of 183 patients with primary malignant tumor of the elderly in our hospital from February 2005 to February 2009 were retrospectively analyzed. SPSS software was used to analyze the related factors that affect the prognosis of elderly patients with primary malignant tumor. Results The incidence rates of esophageal cancer, lung cancer, liver cancer and gastric cancer in primary malignant tumors were higher than those in primary tumors. The overall survival rates of patients at 12 months, 24 months and 36 months were 52.5%, 15.3% and 2.7%, respectively. 1.8% of liver cancer patients treated with anti-tumor, 81.8% gave up anti-tumor therapy. 95.7% of cancer patients were treated with anti-tumor therapy for 1-2 cycles without complete tumor comprehensive treatment. Univariate analysis of age-related malignancies awareness, economic factors, whether the standardization and individual comprehensive treatment, sex, age, tumor staging and complications are the prognosis of elderly malignant tumor prognosis survival of the main factors related to multivariate analysis The awareness of elderly malignant tumors, economic factors, whether the standardization and individual comprehensive treatment is an independent prognostic factor for the prognosis of elderly malignant tumors. Conclusion The cognition and economic factors of elderly malignant tumors are the most important factors affecting the prognosis of elderly malignant tumors. The standardization and individualized mastery of primary medical doctors on the treatment of elderly malignant tumors are also important factors in the prevention of primary malignant tumors . Sex, age, comorbidities, pathological types and staging of malignant tumors are the related factors that affect the prognosis of elderly malignant tumors. To strengthen the knowledge of elderly malignant tumors missionary and grassroots oncologists standardization and individualized treatment of professional knowledge training is the top priority for the treatment of elderly patients with malignant tumors.