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目的研究完整结肠系膜切除治疗老年肥胖患者结肠癌的临床效果。方法 100例老年肥胖结肠癌患者,将其随机分为观察组及对照组,各50例。观察组实行完整结肠系膜切除治疗,对照组实行结肠癌根治术,对比两组患者的临床疗效、住院时间、手术时间、术中出血量、淋巴结清扫数量及并发症发生率。结果观察组患者总有效率94%高于对照组80%,差异具有统计学意义(χ~2=4.3324,P<0.05)。观察组患者住院时间为(8.3±2.4)d,手术时间为(165.3±20.8)min,术中出血量为(82.4±15.6)ml,淋巴结清扫数量为(26.3±4.6)枚,与对照组的(11.6±1.8)d、(152.3±22.6)min、(96.4±17.3)ml、(14.9±3.7)枚比较,差异均具有统计学意义(t=7.7782、2.9928、4.2497、13.6549,P<0.05)。观察组患者并发症发生率4%低于对照组18%,差异具有统计学意义(χ~2=5.0051,P<0.05)。结论对老年肥胖结肠癌患者实行完整结肠系膜切除治疗效果明显,有效减少患者的出血量,值得临床推广。
Objective To study the clinical effect of complete mesorectal excision on the treatment of colon cancer in elderly obese patients. Methods A total of 100 elderly patients with obesity and colon cancer were randomly divided into observation group and control group, 50 cases each. The observation group was treated with complete mesorectal excision, and the control group was treated with radical resection of colon cancer. The clinical efficacy, hospitalization time, operation time, intraoperative blood loss, lymph node dissection and complication rates were compared between the two groups. Results The total effective rate in the observation group was 94% higher than that in the control group (80%), the difference was statistically significant (χ ~ 2 = 4.3324, P <0.05). The hospitalization time was (8.3 ± 2.4) days and the operation time was (165.3 ± 20.8) min in the observation group, the blood loss was (82.4 ± 15.6) ml and the number of lymph node dissection was (26.3 ± 4.6) (11.6 ± 1.8) days, (152.3 ± 22.6) min, (96.4 ± 17.3) ml and (14.9 ± 3.7) days respectively. There were significant differences between the two groups (t = 7.7782,2.9928,4.2497,13.6549, P <0.05) . The incidence of complication in the observation group was 4% lower than that in the control group (χ ~ 2 = 5.0051, P <0.05). Conclusion The treatment of elderly patients with obese colon cancer with complete mesorectal excision is effective and can effectively reduce the amount of bleeding in patients. It deserves clinical promotion.