本综合征是指极度肥胖患者在没有原发心脏或肺脏疾病情况下,发生肺泡换气低下所产生的一系列症状,如呼吸困难、心功能不全、嗜睡等。若将体重减轻,临床症状即可明显好转。本综合征多见于中午以后的成年人,儿童则较少见。本征首先由Burwell氏(1956)命名为Pickwickian综合征。以后陆续有类似病例报告,并对其发病机理作了进一步探讨。临床表现Burwell氏在最初称本征为肥胖性心脏病,并指 The syndrome refers to a series of symptoms of obstructive alveolar hypoventilation in extremely obese patients in the absence of primary heart or lung disease such as dyspnea, cardiac insufficiency, drowsiness and the like. If the weight loss, clinical symptoms can be significantly improved. The syndrome more common in adults after noon, children are less common. The eigenvector was first named Pickwickian syndrome by Burwell’s (1956). After one after another similar case reports, and its pathogenesis was further explored. Burwell’s clinical presentation was originally described as intrinsic for obesity and refers to heart disease