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实验证明~(60)Cor线照射血浆能诱发正常人淋巴细胞微核率增高,且与受照剂量呈直线相关,回归方程y=2.289+0.023x。提示通常所见到的整体或离体照射后微核率增高额应为射线直接效应加照射血浆间接效应的总和。受照血浆诱发的微核率随血浆照射剂量加大而增高,但这种间接效应的微核率增高趋势较缓,随着照射剂量增加,在总和微核率中间接效应所致微核率的比例越来越小,与照射剂量呈负相关(r=-0.9588)。因此在100R左右较低剂量照射时,由受照血浆诱发微核的间接效应,在总和微核率中所占比重较大,约占1/2左右。本文最后提出,对小剂量直接照射人离体血诱发淋巴细胞微核的来源问题似应重新认识。
Experiments show that ~ (60) Cor line irradiated plasma can induce normal human lymphocyte micronucleus rate increased, and the dose was a linear correlation, the regression equation y = 2.289 + 0.023x. It is suggested that the increase in micronucleus rate, as a general rule, after exposure to whole or isolated radiation should be the sum of the direct effect of radiation and the indirect effect of irradiated plasma. The micronucleus rate of irradiated plasma increased with the increase of plasma irradiation dosage, but the increase of micronucleus rate of this indirect effect tended to be slow. With the increase of irradiation dosage, the micronucleus rate in the sum of micronucleus rate Smaller and smaller, with the dose was negatively correlated (r = -0.9588). Therefore, when the dose of 100R is lower, the indirect effect of micronucleus induced by irradiated plasma accounts for a large proportion of the total micronucleus rate, accounting for about 1/2. Finally, this paper proposed that the direct exposure of small doses of human blood-induced lymphocyte micronucleus source should be re-recognized.