Shy-Drager综合征为一种体位性低血压伴其他自主神经症状的疾病,报告1例如下。患者男,54岁,头晕、步态不稳、口齿不清进行性加重2年,于1991年6月29日入院。病人于2年前骑自行车时突然头晕,两眼视物模糊,脸色苍白,方向不能控制,以后不再骑车。并在突然起坐行走时昏厥发作数次。无恶心、呕吐、耳鸣、耳聋等症状。以“椎-基动脉供血不足”治疗,效果不明显。10个月后,步态呈酒醉状,并有头重脚轻感、全身出汗、发音低钝、阳萎、尿急等症状。无急慢性传染病史,既往身体健康。无烟酒嗜好。家属中无类似病史。体检:BP21/12kPa(卧),12/7kPa(坐)。多次检查均一样。神经系统:发音低,颅神经(-),无眼颤,眼底(-),颈无抵抗。四肢肌肉:两上肢二、三头肌及前臂肌轻度萎缩,两下肢股四头肌及腓肠肌等轻皮萎缩。肌力Ⅴ级。四肢 Shy-Drager syndrome is a type of orthostatic hypotension with other autonomic symptoms of the disease, one reported as follows. Male, 54 years old, dizzy, unsteady gait, slurred speech 2 years, admitted to hospital on June 29, 1991. The patient suddenly dizzy while riding a bicycle two years ago, his eyes were blurred, his face pale, his direction incapable of being controlled and he no longer cycled. And in a sudden sit-ups, fainting several times. No nausea, vomiting, tinnitus, deafness and other symptoms. To “vertebrobasilar insufficiency” treatment, the effect is not obvious. Ten months later, the gait was drunk and had top-heavy feet, sweating, low bluntness, impotence, urgency and other symptoms. No history of acute and chronic infectious diseases, previous physical health. Non-smoking alcohol hobby. No similar family history of illness. Physical examination: BP21 / 12kPa (lying), 12 / 7kPa (sitting). Multiple checks are the same. Nervous system: low articulation, cranial nerves (-), nystagmus, fundus (-), neck non-resistant. Limbs and muscles: two upper and lower limbs, triceps and forearm muscle mild atrophy, lower limb quadriceps and gastrocnemius and other skin atrophy. Grade Ⅴ muscle strength. Limbs