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目的探讨胎儿硬腭/牙槽骨的三维超声检查方法并评价其测量方法。方法采集14例11+0～13+6周胎儿颜面部的三维容积数据,旋转X、Y、Z轴并调整感兴趣区获取含硬腭/牙槽骨的容积层,运用混合重建模式显示硬腭/牙槽骨的形态,并对硬腭/牙槽骨的整体长度和宽度进行重复测量。结果 14例胎儿硬腭/牙槽骨整体显示率为100%。单一容积数据重复测量的硬腭/牙槽骨整体长的差值均值为-0.09mm,95%一致性界限为-0.40～0.21mm,宽的差值均值为-0.08mm,95%一致性界限为-0.72～0.56mm。不同容积数据重复测量的硬腭/牙槽骨整体长的差值均值为-0.14mm,95%一致性界限为-0.75～0.46mm,宽的差值均值为0.11mm,95%一致性界限为-1.23～1.46mm。结论 11+0～13+6周应用三维超声检查胎儿硬腭/牙槽骨发育简便可行,相关测量可重复性较好,可应用于临床。
Objective To investigate the method of three-dimensional ultrasonography of fetal hard palate and alveolar bone and to evaluate its measurement method. Methods Three-dimensional volume data of 14 facial fetuses from 11 + 0 to 13 + 6 weeks were acquired. The X, Y and Z axes were rotated and the region of interest was adjusted to obtain the volumetric layer with hard palate / alveolar bone. Alveolar bone morphology, and the overall length and width of the hard palate / alveolar bone repeated measurements. Results Fourteen cases of fetal hard palate / alveolar bone showed a 100% overall rate. The mean value of the total length of the hard palate / alveolar bone measured repeatedly in a single volumetric data was -0.09 mm, the 95% agreement margin was -0.40 to 0.21 mm, the wide difference mean value was -0.08 mm, and the 95% agreement margin was -0.72 ~ 0.56mm. The mean value of the overall long palatal / alveolar bone differential measured by different volumes of data was -0.14 mm, the 95% agreement margin was -0.75-0.46 mm, the wide difference mean value was 0.11 mm, and the 95% agreement margin was - 1.23 ~ 1.46mm. Conclusion The development of fetal hard palate and alveolar bone in 11 + 0 ~ 13 + 6 weeks with simple three-dimensional sonography is simple and feasible. The reproducibility of the related measurements is good and can be applied to clinic.