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目的探讨生殖道解脲支原体(ureaplasm urealyticum,UU)和沙眼衣原体(chlamydia trachomatis,CT)感染与女性不孕的关系。方法于妇科门诊整群抽取238例不孕症患者作为实验组,同法抽取产后42天来院体检,自愿进行UU-DNA及CT-DNA检测的240例妇女为正常对照组;采用PCR法检测正常对照组和实验组女性UU-DNA及CT-DNA。结果与正常对照组相比,不孕组女性UU-DNA阳性率高于正常对照组(P<0.001),不孕组中原发性不孕组与继发性不孕组UU-DNA阳性率差异有统计学意义(P<0.001);不孕组与正常对照组相比,原发性不孕组与继发性不孕组相比,CT-DNA阳性率差异均无统计学意义(均有P>0.05)。结论 UU感染可能与不孕症密切相关,故需在已婚育龄夫妇中加强UU感染监测及防治,降低不孕症发生率。
Objective To investigate the relationship between genital tract ureaplasma urealyticum (UU) and chlamydia trachomatis (CT) infection and female infertility. Methods A total of 238 cases of infertility were selected as the experimental group in the gynecology outpatient group. 240 women who took UU-DNA and CT-DNA tests 42 days after delivery were selected as the normal control group. The normal Control group and experimental group of female UU-DNA and CT-DNA. Results The positive rate of UU-DNA in infertile women was significantly higher than that in normal controls (P <0.001). The positive rate of UU-DNA in infertile women and secondary infertile women (P <0.001). Compared with the normal control group, there was no significant difference in the positive rate of CT-DNA between the infertility group and the secondary infertile group (both P> 0.05). Conclusion UU infection may be closely related to infertility. Therefore, it is necessary to strengthen the surveillance and prevention of UU infection among married couples of childbearing age and reduce the incidence of infertility.