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目的观察EP方案配合参芪扶正注射液对小细胞肺癌患者实体瘤客观疗效评定标准(RECIST)及生活质量(KPS评分)的影响。方法将90例小细胞肺癌患者随机分为观察组与对照组,均予相应化疗方案,观察组加用参芪扶正注射液;两组均以21d为1周期,2个周期后评判疗效。结果观察组患者临床疗效优于对照组,但无显著性差异(P>0.05)。观察组在生活质量、化疗毒副反应改善等方面明显优于对照组(P<0.05)。结论参芪扶正注射液辅助化疗能改善小细胞肺癌患者的生活质量,减少并发症,值得临床推广应用。
Objective To observe the effect of EP regimen and Shenqi Fuzheng injection on RECIST and KPS scores of solid tumor in patients with small cell lung cancer. Methods Ninety patients with small cell lung cancer were randomly divided into the observation group and the control group. All the patients were given the corresponding chemotherapy regimen. The observation group and the Shenqi Fuzheng injection were used. Both groups were given 21 cycles of 1 cycle and 2 cycles later. Results The clinical efficacy of the observation group was better than that of the control group, but no significant difference (P> 0.05). The observation group was significantly better than the control group in terms of quality of life, improvement of chemotherapy side effects (P <0.05). Conclusion Shenqi Fuzheng injection adjuvant chemotherapy can improve the quality of life of patients with small cell lung cancer and reduce complications, worthy of clinical application.