Ⅰ、全肺灌洗用于矽肺、石棉肺与铸工尘肺的治疗经纤支镜取矽肺病人的肺活检材料证实在肺间质内游离SiO_2含量极少,绝大多数存在于肺泡腔的肺泡巨噬细胞(AM)内。而这些生活着的含矽AM又能分泌多种致纤维化的介质如纤维联结蛋白(FN)与肺泡巨噬细胞衍化生长因子(AMDGF)等,可促进纤维母细胞生长、增殖,故通过全肺灌洗 Ⅰ, the whole lung lavage for the treatment of silicosis, asbestosis and cast iron pneumoconiosis Lung biopsy material taken by patients with silicosis by fiberoptic bronchoscopy confirmed that there is very little free SiO2 in the interstitial lung, the vast majority of alveolar giant Within the macrophage (AM). And these living silicon containing AM can secrete a variety of fibrinolytic mediators such as fibronectin (FN) and alveolar macrophage-derived growth factor (AMDGF), etc., can promote fibroblast growth and proliferation, so through the whole Lung lavage