虽然已知抗组胺类药物可局部应用于过敏性结膜炎,但由于局部刺激、缺乏疗效和担心过敏反应,仅有少数药物可供选用,且不普遍。Levocabastine具有很强的H受体拮抗作用,起效快,且有显著的组胺专一性。本品局部应用于防护眼和鼻粘膜不受组胺和过敏原刺激的剂量极低,仅为0.05mg,现已有相应的制剂作眼和鼻内应用。 Although antihistamines are known to be applied topically to allergic conjunctivitis, only a few drugs are available for selection due to local irritation, lack of efficacy and fear of anaphylaxis, and are uncommon. Levocabastine has a strong H receptor antagonism, rapid onset, and significant histamine specificity. This product is partially used in the prevention of eye and nasal mucosa histamine and allergen stimulation dose is very low, only 0.05mg, there are already the corresponding preparations for eye and nose applications.