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目的探索米非司酮配伍米索前列醇在中期妊娠引产中的临床应用价值。方法选择我院2009年1月至2011年12月的12～27周自愿终止妊娠孕妇,口服米非司酮配伍米索前列醇100例,经腹壁羊膜腔穿刺注入依沙吖定80例进行对比分析,观察两组的总产程,胎儿胎盘娩出时间,宫内残留率,产后2h出血量,引产成功率,并发症,药物副反应。结果观察组总产程,产后出血量,宫内残留率等均小于对照组。结论米非司酮配伍米索前列醇用于中期妊娠引产,能有效缩短产程,减少出血量及宫内残留率,药物副反应可通过改变用药方法降低。
Objective To explore the clinical value of mifepristone combined with misoprostol in induction of labor in the second trimester of pregnancy. Methods A total of 100 pregnant women with voluntary termination of pregnancy during the first 12-27 weeks of our hospital from January 2009 to December 2011 were enrolled. 100 cases were treated with mifepristone and misoprostol, and 80 cases were treated by amniocentesis by amniocentesis Analysis and observation of two groups of total labor, fetal placenta delivery time, intrauterine residual rate, 2h postpartum hemorrhage, induction of labor success rate, complications, drug side effects. Results The observation group, total labor, postpartum hemorrhage, intrauterine residual rate were less than the control group. Conclusion Mifepristone combined with misoprostol for induction of labor in the second trimester of pregnancy can effectively shorten the labor process and reduce the amount of bleeding and intrauterine residual rate, drug side effects can be reduced by changing the method of medication.