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目的探讨宫颈上皮内瘤变(CIN)临床诊断及治疗效果。方法选择本院2012年1月~2013年12月经门诊液基薄层细胞学(TCT)检测,后经电子阴道镜下多点活检诊断CIN患者,阅片时病理诊断采用三级分类法共156例进行回顾性分析。结果 156例患者中两种方法的病理组织学检查报告升级49例,占31.41%。113例CIN患者中,HPV感染者占82.30%,其中CIN I中10例,阳性率为71.43%;CINⅡ中48例,阳性率为78.69%;CINⅢ中有35例,阳性率达92.11%。随着CIN级别的增高,HPV感染的几率也随之增高。结论宫颈细胞学检查结合阴道镜检是诊断CIN的有效方法 ,CIN及其级别与HPV感染之间有重要关系。对不宜手术的原位癌患者可行单纯腔内放疗。
Objective To investigate the clinical diagnosis and treatment of cervical intraepithelial neoplasia (CIN). Methods The hospital from 2012 January to 2013 December by the clinic liquid-based thin-layer cytology (TCT) detection, after multi-point biopsy by electronic colposcopy in patients with CIN, pathological diagnosis when reading using three-class classification of a total of 156 Cases were retrospectively analyzed. Results Among the 156 patients, 49 cases (31.41%) were upgraded with histopathological examination of the two methods. In 113 CIN patients, HPV infection accounted for 82.30%, of which 10 cases of CIN I, the positive rate was 71.43%; 48 cases of CIN Ⅱ, the positive rate was 78.69%; CIN Ⅲ in 35 cases, the positive rate of 92.11%. With the CIN level increased, the risk of HPV infection also increased. Conclusion Cervical cytology combined with colposcopy is an effective method to diagnose CIN. There is an important relationship between CIN and its grade and HPV infection. Inoperable in situ carcinoma of patients with viable only cavity radiotherapy.