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采用ＲＮＡ斑点杂交技术，应用地高辛标记的ｃｆｏｓ基因探针检测培养的兔动脉平滑肌细胞中ｃｆｏｓｍＲＮＡ水平。结果显示绞股蓝总甙对ｃｆｏｓ基因甙的表达有抑制作用（Ｐ＜０．０１）；并且与绞股蓝总甙浓度呈依赖性负相关。推测绞股蓝总甙可能对动脉平滑肌细胞有抑制增生的药理作用。
Using RNA dot blot hybridization, digoxin labeled c fos gene probe c rabbit vascular smooth muscle cells cultured c fos mRNA levels. The results showed that Gypenosides inhibited the expression of c-fos gene glycosides (P <0.01), and was negatively correlated with the concentration of gypenosides. Presumably gypenosides may inhibit arterial smooth muscle cell proliferation and pharmacological effects.