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目的:评价左氧氟沙星与百令胶囊联用对慢性肾衰竭血液透析患者下呼吸道感染的疗效及其对免疫学指标的影响。方法:选取2014年2月—2016年2月间收治的慢性肾衰竭血液透析并发下呼吸道感染患者90例,将其分为观察组和对照组,每组45例;对照组患者给予左氧氟沙星治疗,观察组患者在对照组基础上加用百令胶囊治疗,评价两组患者治疗后的疗效及其对免疫学指标的影响。结果:观察组患者治疗后的总有效率为93.33%高于对照组为75.56%(P<0.05),细菌清除率为88.89%高于对照组为60.00%(P<0.05),各免疫指标(CD4、CD4/CD8)治疗后测得值高于对照组(P<0.05)。结论:对慢性肾衰竭血液透析患者下呼吸道感染的药物治疗时,采用百令胶囊与左氧氟沙星联用治疗的疗效以及对较高的细菌清除率。
Objective: To evaluate the efficacy of levofloxacin combined with Bailing capsule on lower respiratory tract infection in patients with chronic renal failure and on the immunological parameters. Methods: A total of 90 patients with chronic respiratory failure who underwent chronic hemodialysis were enrolled in the study. Patients in the control group were treated with levofloxacin, Patients in the observation group were treated with Bailing capsule on the basis of the control group, and the therapeutic effect and the influence on the immunological indexes of the two groups were evaluated. Results: The total effective rate of the observation group after treatment was 93.33% higher than that of the control group (75.56%, P <0.05), the bacterial clearance rate was 88.89% higher than that of the control group (60.00%, P <0.05) CD4, CD4 / CD8) after treatment was higher than the control group (P <0.05). Conclusion: The therapeutic effect of Bailing capsule combined with levofloxacin and the high bacterial clearance rate in the treatment of lower respiratory tract infection in hemodialysis patients with chronic renal failure.