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本文采用随机分组法，观察施他宁治疗食管静脉曲张破裂出血的疗效，并与垂体后叶素对照，结果发现施他宁有效率85％，垂体后叶素有效率55％。经X2检验，两者相差非常显著，结论是施他宁能选择性减少内脏血流量，降低肝内血管阻力，增加食道下段括约肌张力，对胰腺、小肠和肝脏细胞有保护作用，是治疗肝硬变食管静脉曲张破裂出血的一种有前途的药物，可望取代垂体后叶素。
In this paper, a randomized grouping method was used to observe the curative effect of Sitatin’s treatment of esophageal variceal bleeding, and compared with pituitrin, the results showed that the effective rate was 85% and the effective rate of pituitrin was 55%. By X2 test, the difference between the two is very significant, the conclusion is that Sitatin can selectively reduce visceral blood flow, reduce intrahepatic vascular resistance, increased esophageal sphincter tension, the pancreas, small intestine and liver cells have a protective effect, is the treatment of liver cirrhosis A promising drug for esophageal variceal bleeding that is expected to replace vasopressin.