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目的比较不同剂量地佐辛联合丙泊酚静脉麻醉在人工流产术中的应用效果。方法选取漳州市人民医院妇产科2014年6月—2016年6月收治的行无痛人工流产术患者94例,随机分为A组(n=33)、B组(n=32)、C组(n=29)。术前给予常规辅助检查,禁饮禁食。进入手术室后,快速建立静脉通路,在麻醉诱导前均给予地佐辛静脉注射,A组使用剂量为0.050 mg/kg,B组为0.075 mg/kg,C组为0.100 mg/kg,而后缓慢静脉注射丙泊酚。比较3组患者丙泊酚用量、麻醉起效时间、苏醒时间及不良反应情况。结果 B、C组患者丙泊酚用量少于A组,麻醉起效时间、术后苏醒时间短于A组(P<0.05);B组和C组患者丙泊酚用量、麻醉起效时间、术后苏醒时间比较,差异无统计学意义(P>0.05)。B组患者不良反应发生率低于A、C组(P<0.05);A组和C组患者不良反应发生率比较,差异无统计学意义(P<0.05)。结论剂量为0.075 mg/kg地佐辛联合丙泊酚静脉麻醉在人工流产术中应用效果最佳,可减少术中丙泊酚用量,缩短麻醉起效时间及术后苏醒时间,降低不良反应发生率。
Objective To compare the effects of different doses of dezocine plus propofol intravenous anesthesia in artificial abortion. Methods Ninety-four patients undergoing painless abortion underwent surgery from June 2014 to June 2016 in Zhangzhou People’s Hospital were randomly divided into three groups: group A (n = 33), group B (n = 32), group C Group (n = 29). Preoperative routine auxiliary examination, fasting ban fasting. Into the operating room, the rapid establishment of venous access, before induction of anesthesia were given dexrazoxane intravenous injection, the dose of 0.050 mg / kg in group A, 0.075 mg / kg in group B, 0.100 mg / kg in group C, and then slowly Intravenous propofol. Propofol dosage, anesthesia onset time, recovery time and adverse reactions were compared between the three groups. Results The dosage of propofol in group B and C was less than that in group A, the onset time of anesthesia and the recovery time were shorter than those in group A (P <0.05). The dosage of propofol in group B and group C, There was no significant difference in the recovery time after operation (P> 0.05). The incidence of adverse reactions in group B was lower than that in group A and C (P <0.05). There was no significant difference in the incidence of adverse reactions between group A and group C (P <0.05). Conclusion The combination of dezocine and propofol intravenous anesthesia with 0.075 mg / kg intravenous anesthesia has the best effect in induced abortion, which can reduce the intraoperative propofol dosage, shorten the onset time of anesthesia and postoperative recovery time, and reduce the incidence of adverse reactions rate.