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氟哌啶醇系丁酰苯类抗精神常药的代表,由于对心血管系统、肝脏毒性较小,常用于年老体弱及伴随躯体疾病患者.其常见不良反应为锥体外系作用,偶见心动过速.心动过缓甚少.但我们两所医院在1994～1997年188例服用氟哌啶醇的住院患者中出现6例心动过缓.临床资料 一般情况:6例患者均系单用抗精神病药物氟哌啶醇治疗(上海黄河制药厂,批号:940401),使用剂量(21.7±4.6)mg/d(18～28mp/ d),均合并盐酸苯海索片4mg/d,5例合并VitB_1 40mg/d,4例合并VitB_6 60mg/d;其中男性2例.女性例心动过缓.临床资料 一般情况:6例患者均系单用抗精神病药物氟哌啶醇治疗(上海黄河制药厂,批号:940401),使用剂量(21.7±4.6)mg/d(18～28mp/ d),均合并盐酸苯海索片4mg/d,5例合并VitB_1 40mg/d,4例合并VitB_6 60mg/d;其中男性2例.女性
Haloperidol, the representative of butyrophenone antipsychotics, is less commonly used in patients with frailty and associated with somatic diseases because of its less cardiovascular and liver toxicity, and its common adverse effects are extrapyramidal action and even See Tachycardia. Bradycardia rarely, but in our two hospitals 188 cases of haloperidol in hospitalized patients in 1994 to 1997, there were 6 cases of bradycardia. Clinical data General situation: 6 patients were single With the antipsychotics haloperidol treatment (Shanghai Yellow River Pharmaceutical Factory, batch number: 940401), the use of dose (21.7 ± 4.6) mg / d (18 ~ 28mp / d) Cases of combined VitB_1 40mg / d, 4 cases of combined VitB_6 60mg / d; of which 2 males .Female bradycardia clinical data General situation: 6 patients were treated with antipsychotics haloperidol alone (Shanghai Huanghe Pharmaceutical The results showed that there was no significant difference between the two groups (P <0.05). The dosage was (21.7 ± 4.6) mg / d (18-28 mp / d) d; male of which 2 cases