前言针麻临床和动物实验的研究表明,针刺镇痛效应与神经和体液因素的变化有关。研究在针刺的作用下,参与镇痛的神经结构,递质和体液因素的作用机制,不仅对阐明针麻原理有着重大意义,而且通过进一步改变这些神经结构、递质和体液因素的机能状态,对于解决针麻“三关”问题,提高针麻效果,可以提供有效的途径。大量的实验证明,环一磷酸腺苷对各种不同动物的各种不同组织的代谢与生理功能的调节起着重要的作用。它作为第二信使,参与神经系统的突触传递和激素合成、释放及其生理作用过程。因此,针麻过程中环一磷酸腺苷在有关器官组织中的变化,以及外源性 cAMP 的 Introduction Acupuncture anesthesia clinical and animal studies have shown that acupuncture analgesic effect and nerve and body fluid changes. Studying the mechanism of acupuncture in the neuro-structure, neurotransmitter and humoral factors involved in analgesia is of great significance not only to clarify the principle of acupuncture anesthesia, but also to further change the functional status of these neurological structures, neurotransmitters and humoral factors , For resolving Acupuncture Ma “three off” problem, improve acne effect, can provide an effective way. A large number of experiments show that cyclic adenosine monophosphate (AMPA) plays an important role in the regulation of metabolism and physiological functions of various tissues in different kinds of animals. As a second messenger, it participates in synaptic transmission and hormone synthesis, release and physiological processes in the nervous system. Therefore, acanthosis during the cyclic adenosine monophosphate in the relevant organ tissue changes, as well as exogenous cAMP